Acute Renal Failure in children with Diabetic ketoacidosis
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چکیده
Acute renal failure is an uncommon complication among children with Diabetic keto acidosis. This has been recently reported from developing countries. Prerenal uremia which improves in few hours is common in DKA and this is fluid responsive, however intrinsic renal failure with increasing urea creatinine and anuria is associated with high mortality and is uncommon. Sepsis, shock, severe dehydration, rhabdomyolysis and thrombotic microangiopathic syndrome are the underlying factors for acute renal failure in children with DKA. The incidence of acute renal failure varies from 3.7% to 11.5%. Management includes change in fluid electrolyte therapy, insulin dose, bicarbonate infusion and renal replacement therapy in the form of hemodialysis or peritoneal dialysis. Mortality in acute renal failure in DKA varies from 40 72%. Earlier identification of renal failure is mandatory for a better outcome.
منابع مشابه
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